| Identification | Back Directory | [Name]
2-Fluoro-5-methoxy-4-nitrobenzoic acid | [CAS]
1001345-80-7 | [Synonyms]
2-Fluoro-5-methoxy-4-nitrobenzoic acid
Benzoic acid, 2-fluoro-5-methoxy-4-nitro- | [Molecular Formula]
C8H6FNO5 | [MDL Number]
MFCD26395470 | [MOL File]
1001345-80-7.mol | [Molecular Weight]
215.14 |
| Hazard Information | Back Directory | [Synthesis]
2-Fluoro-5-methoxy-4-nitrobenzoic acid can be synthesized using various methods such as the Friedel-Crafts acylation reaction, the Suzuki-Miyaura coupling reaction, and the Buchwald-Hartwig amination reaction. The Friedel-Crafts acylation reaction involves the reaction of 2-fluoro-5-methoxy-4-nitrobenzoyl chloride with methanol in the presence of a catalyst such as aluminum chloride. The Suzuki-Miyaura coupling reaction involves the reaction of 2-fluoro-5-methoxy-4-nitrophenylboronic acid with 4-chlorobenzoic acid in the presence of a palladium catalyst. The Buchwald-Hartwig amination reaction involves the reaction of 2-fluoro-5-methoxy-4-nitroiodobenzene with potassium phthalimide in the presence of a palladium catalyst. |
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