| Identification | Back Directory | [Name]
Niraparib metabolite M1 | [CAS]
1476777-06-6 | [Synonyms]
Niraparib Impurity 1
Niraparib metabolite M1
Niraparib Carboxylic Acid
M1 metabolite of niraparib
Niraparib Metabolite M1 hydrochloride
Niraparib carboxylic acid metabolite M1
2H-Indazole-7-carboxylic acid, 2-[4-(3S)-3-piperidinylphenyl]- | [Molecular Formula]
C19H19N3O2 | [MDL Number]
MFCD30534402 | [MOL File]
1476777-06-6.mol | [Molecular Weight]
321.37 |
| Chemical Properties | Back Directory | [Boiling point ]
442.0±45.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (311.17 mM) | [pka]
-2.18±0.30(Predicted) |
| Hazard Information | Back Directory | [Uses]
Niraparib Carboxylic Acid is an impurity of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. |
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