Identification | Back Directory | [Name]
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole | [CAS]
457961-34-1 | [Synonyms]
Cy1001 AA92593 AA92593 >=98% (HPLC) 1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine 1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]- 4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole | [Molecular Formula]
C13H19NO3S | [MOL File]
457961-34-1.mol | [Molecular Weight]
269.36 |
Hazard Information | Back Directory | [Uses]
AA92593 has been used as a selective melanopsin inhibitor. | [Biochem/physiol Actions]
AA92593 is an opsinamide, a potent antagonist of melanopsin-mediated phototransduction with an IC50 of 665 nM in a Ca2+ flux assay in CHO cells expressing melanopsin (Opn4) and selectivity > 10 μM at 74 common biological targets. AA41612 is believed to act by competing for binding to melanopsin. AA41612 inhibited mouse pupillary light reflex and light aversion in vivo. AA92593 and similar compounds might be useful in alleviating the photophobia associated with migraine. | [storage]
Store at -20°C |
|
Company Name: |
|
Tel: |
021-61415566 800-8193336 |
Website: |
//www.sigmaaldrich.cn |
Company Name: |
|
Tel: |
021-52996696,15000506266 15000506266 |
Website: |
//www.bioll.com |
Company Name: |
|
Tel: |
+86-400-851-9921 |
Website: |
www.pharmacodia.com |
Company Name: |
|
Tel: |
021-65675885 18964387627 |
Website: |
//www.efebio.com |
Company Name: |
|
Tel: |
21-31433387 15618786686 |
Website: |
cn.rechemscience.com |
Company Name: |
|
Tel: |
86-(0)29-85992781 17792393971 |
Website: |
//www.lynnchem.com/ |
Company Name: |
|
Tel: |
44-20819178-90 02081917890 |
Website: |
//www.novachemistry.com/ |
Company Name: |
DC Chemicals
|
Tel: |
021-58447131 13564518121 |
Website: |
//bestpetlove.com/ShowSupplierProductsList927327/0.htm |
Company Name: |
|
Tel: |
0519-85788828 13775037613 |
Website: |
//www.chemrenblock.com/ |
|