ChemicalBook >> CAS DataBase List >>2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
- CAS No.
- 194085-75-1
- Chemical Name:
- 2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
- Synonyms
- YKP 509;RWJ 333369;Carisbamate;JNJ 10234094;(S)-Carisbamate;CarisbaMate (RWJ-333369);2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE;[(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate;1,2-ETHANEDIOL,1-(2-CHLOROPHENYL)-, 2-CARBAMATE, (S)-;1,2-Ethanediol,1-(2-chlorophenyl)-, 2-carbaMate, (1S)-
- CBNumber:
- CB11474577
- Molecular Formula:
- C813CH8D2Cl15NO3
- Molecular Weight:
- 215.63
- MDL Number:
- MFCD15071195
- MOL File:
- 194085-75-1.mol
- MSDS File:
- SDS
Last updated:2024-05-18 11:31:10
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23514 | Carisbamate ≥98% | 194085-75-1 | 500μg | $121 | 2025-03-01 | Buy |
| Cayman Chemical | 23514 | Carisbamate ≥98% | 194085-75-1 | 1mg | $218 | 2025-03-01 | Buy |
| TRC | C183510 | (S)-Carisbamate | 194085-75-1 | 5mg | $215 | 2022-12-16 | Buy |
| American Custom Chemicals Corporation | API0009416 | CARISBAMATE 95.00% | 194085-75-1 | 1MG | $315 | 2022-12-16 | Buy |
| AK Scientific | X3698 | (S)-Carisbamate | 194085-75-1 | 1mg | $340 | 2022-12-16 | Buy |
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Chemical Properties,Uses,Production
Description
Carisbamate is an antiepileptic agent., In vivo, administration of carisbamate (10-60 mg/kg) dose-dependently reduces spike and wave discharges in the frontoparietal cortex in a rat model of absence seizures. Carisbamate (10 mg/kg) increases latency to the first running episode in the Wistar audiogenic sensitive rat model of convulsive seizures. It also reduces motor seizure frequency in a rat model of spontaneous seizures in a dose-dependent manner. Carisbamate blocks Nav1.2 channels (IC50 = 68 μM for rat channels) and inhibits repetitive firing of action potentials in rat hippocampal neurons in a dose-dependent manner. It also reduces T-type Ca2+ currents in HEK cells transfected with human recombinant Cav3.1 channels at a concentration of 300 μM.
Uses
Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.Uses
Labelled Carisbamate; it is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizu re models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.Definition
ChEBI: Carisbamate is an organochlorine compound.2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7019 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE
Carisbamate
(S)-Carisbamate
1,2-Ethanediol,1-(2-chlorophenyl)-, 2-carbaMate, (1S)-
JNJ 10234094
RWJ 333369
YKP 509
CarisbaMate (RWJ-333369)
[(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate
1,2-ETHANEDIOL,1-(2-CHLOROPHENYL)-, 2-CARBAMATE, (S)-
194085-75-1
C813CH8D2Cl15NO3
Amines
Aromatics
Chiral Reagents
Intermediates & Fine Chemicals
Isotope Labelled Compounds
Pharmaceuticals