ChemicalBook >> CAS DataBase List >>Benzothiazole
Benzothiazole
- CAS No.
- 95-16-9
- Chemical Name:
- Benzothiazole
- Synonyms
- Benzo[d]thiazole;Benzothiazol;1,3-BENZOTHIAZOLE;Vangard BT;o-2857;NSC 8040;vangardbt;FEMA 3256;usafek-4812;USAF ek-4812
- CBNumber:
- CB1720657
- Molecular Formula:
- C7H5NS
- Molecular Weight:
- 135.19
- MDL Number:
- MFCD00005775
- MOL File:
- 95-16-9.mol
- MSDS File:
- SDS
Last updated:2025-03-22 11:43:20
Melting point | 2 °C (lit.) |
---|---|
Boiling point | 231 °C (lit.) |
Density | 1.238 g/mL at 25 °C (lit.) |
vapor density | 4.66 (vs air) |
vapor pressure | 34 mm Hg ( 131 °C) |
refractive index |
n |
FEMA | |
Flash point | >230 °F |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | 3g/l |
form | Liquid |
pka | 0.85±0.10(Predicted) |
color | Clear yellow-brown to brown |
Odor | odor of quinoline, sltly water-sol |
Odor Type | sulfurous |
explosive limit | 0.9-8.2%(V) |
Water Solubility | slightly soluble |
Merck | 14,1107 |
JECFA Number | 1040 |
BRN | 109468 |
Stability | Stable - regarded as highly persistent in the environment. Incompatible with strong oxidizing agents. Combustion products: nitrogen oxides, carbon monoxide, carbon dioxide, sulphur oxides. |
InChIKey | IOJUPLGTWVMSFF-UHFFFAOYSA-N |
LogP | 2.01 |
Substances Added to Food (formerly EAFUS) | |
CAS DataBase Reference | 95-16-9(CAS DataBase Reference) |
EWG's Food Scores | |
FDA UNII | |
NIST Chemistry Reference | |
EPA Substance Registry System |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H301+H311-H319 | |||||||||
Precautionary statements | P264-P270-P280-P301+P310-P302+P352+P312-P305+P351+P338 | |||||||||
Hazard Codes | Xn,T,Xi | |||||||||
Risk Statements | 22-20/21/22-36-25-24-20 | |||||||||
Safety Statements | 23-26-36-36/37-45 | |||||||||
RIDADR | 2810 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | DL0875000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29342080 | |||||||||
Toxicity | LD50 i.v. in mice: 95±3 mg/kg (Domino) | |||||||||
NFPA 704 |
|
Benzothiazole price More Price(32)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 101338 | Benzothiazole 96% | 95-16-9 | 5g | $36.4 | 2025-03-01 | Buy |
Sigma-Aldrich | 101338 | Benzothiazole 96% | 95-16-9 | 100g | $62.4 | 2025-03-01 | Buy |
TCI Chemical | B0092 | Benzothiazole >96.0%(GC) | 95-16-9 | 25mL | $31 | 2025-03-01 | Buy |
TCI Chemical | B0092 | Benzothiazole >96.0%(GC) | 95-16-9 | 100mL | $73 | 2025-03-01 | Buy |
Alfa Aesar | A10380 | Benzothiazole, 97% | 95-16-9 | 50g | $25.3 | 2025-03-01 | Buy |
Benzothiazole Chemical Properties,Uses,Production
Description
Benzothiazole and its derivative are recognized as the most important heterocyclic compounds. This series of compounds is of particular interests. It has various kinds of pharmacological properties and has been included in many kinds of natural products and pharmaceutical agents. The broad spectrum of pharmacological activity in individual benzothiazole derivative enables it to serve as unique and valuable scaffolds for experimental drug design. It is already known that benzothiazole and its derivative has various biological applications including anticancer, antimicrobial, anticonvulsant, antiviral, antidiabetic, antipsychotic, antiinflammatory, analgesic, fungicidal and diuretic. Its derivatives also have many applications in polymer chemistry, dyes, drugs, and silver photography as well as rubber industry.Chemical Properties
yellow liquid with an unpleasant odourChemical Properties
Benzothiazole has a delicate, persistent, rose-like odor similar to that of quinoline.Occurrence
Reported found in apricot, cooked asparagus, mozzarella cheese, skim milk powder, roasted beef, beer, malt whiskey, coconut meat, fresh mango, cooked broccoli and kelp.Uses
It is an interesting carbonyl equivalent and reacts with aldehydes or ketones to generate α-hydroxy carbonyl compounds. Benzothiazole is used as a chemical intermediate in organic synthesis. It is a precursor of rubber accelerators and a component of cyanine dyes. It is also used as a flavoring substance. It is also used as a flavor, antimicrobial agent, and component of cyanine dyes. Its derivatives are used as rubber accelerators.Uses
Various benzothiazole-benzamides synthesized were evaluated for their analgesic and antidepressant activities.Definition
ChEBI: An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.Preparation
By refluxing a mixture of zinc o-aminophenylsulfide and formic acid, followed by steam distillation of the alkalized reaction mixture; by heating formanilid or dimethylaniline with sulfur; by oxidation of 2-mercaptobenzothiazole or of the corresponding disulfide.Aroma threshold values
Detection: 80 to 450 ppbTaste threshold values
Taste characteristics at 3 ppm: meaty, vegetative, brown, cooked, beefy and coffee-like.Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 6559, 1955 DOI:
General Description
Benzothiazole, a volatile sulfur-containing heterocyclic compound, is one of the key odorants of heated milk. It is also reported to occur as a flavor component of miso, coconut meat and cooked-beef.Hazard
Highly toxic by ingestion.Safety Profile
Poison by ingestion,intraperitoneal, intravenous, and possibly other routes.When heated to decomposition it emits very toxic fumesof SOx, CN??, and NOx.References
Gupta, Akhilesh, and S. Rawat. "Synthesis and cyclization of benzothiazole." J. of Current Pharmaceutical Research 3.1 (2010): 13-25.
Keri, Rangappa S., et al. "A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry." European journal of medicinal chemistry 89 (2015): 207-251.
Khokra, Sukhbir L., et al. "Common methods to synthesize benzothiazole derivatives and their medicinal significance: a review." International Journal of Pharmaceutical Sciences and Research 2.6 (2011): 1356.
Benzothiazole Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global( 448)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1009 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12452 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | 15315557071@163.com | China | 527 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 14764 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21700 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Related articles
- Synthesis of Benzothiazole
- Benzothiazole is a conjugated sp2-hybridized bicyclic 10π electron heteroaromatic, constituted by fusion of benzene with the 4....
- Jan 24,2022
View Lastest Price from Benzothiazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2025-03-28 | Benzothiazole
95-16-9
|
US $0.00 / Kg/Drum | 1KG | 99% | 2000mt/year | Jinan Finer Chemical Co., Ltd | ||
2025-03-23 | Benzothiazole
95-16-9
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | ||
2024-12-25 | Benzothiazole
95-16-9
|
US $0.00 / kg | 1kg | 99% | 1000000 | Hebei Jingbo New Material Technology Co., Ltd |
- Benzothiazole
95-16-9
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
- Benzothiazole
95-16-9
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
- Benzothiazole
95-16-9
- US $0.00 / kg
- 99%
- Hebei Jingbo New Material Technology Co., Ltd
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Manufacturer Supply High Quality in Stock Benzothiazole CAS?95-16-9
TIANFU CHEM----Benzothiazole
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C13H18BNO3S
C7H5N1S1
C13H16BNO2S
-C6H4NCHS
C7H5NS
Thiazoles
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