ChemicalBook >> CAS DataBase List >>PCI 34051
PCI 34051
- CAS No.
- 950762-95-5
- Chemical Name:
- PCI 34051
- Synonyms
- PCI-34051;PCI 34051;PCI-34051;PCI 34051;N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide;N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide;1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-
- CBNumber:
- CB52622953
- Molecular Formula:
- C17H16N2O3
- Molecular Weight:
- 296.32
- MDL Number:
- MFCD11114393
- MOL File:
- 950762-95-5.mol
- MSDS File:
- SDS
Last updated:2024-06-30 15:45:59
PCI 34051 price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10444 | PCI 34051 ≥95% | 950762-95-5 | 5mg | $77 | 2025-03-01 | Buy |
| Cayman Chemical | 10444 | PCI 34051 ≥95% | 950762-95-5 | 10mg | $144 | 2025-03-01 | Buy |
| Cayman Chemical | 10444 | PCI 34051 ≥95% | 950762-95-5 | 50mg | $602 | 2025-03-01 | Buy |
| Cayman Chemical | 10444 | PCI 34051 ≥95% | 950762-95-5 | 100mg | $829 | 2025-03-01 | Buy |
| Tocris | 4643 | PCI34051 ≥98%(HPLC) | 950762-95-5 | 50 | $471 | 2022-12-16 | Buy |
PCI 34051 Chemical Properties,Uses,Production
Uses
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.Definition
ChEBI: N-hydroxy-1-[(4-methoxyphenyl)methyl]-6-indolecarboxamide is an indolecarboxamide.Biological Activity
pci-34051 is a potent, specific inhibitor of histone deacetylase 8 (hdac8) with greater than 200-fold selectivity over the other hdac isoforms, such as 1, 2, 3, 6 and 10. it induces caspase dependent apoptosis in cell lines derived from t-cell lymphomas or leukemias, but not in other hematopoietic or solid tumor lines. pci-34051 does not cause detectable histone or tubulin acetylation and also does not inhibit growth or induce apoptosis in normal cells such as pbmcs or fibroblasts. although a phospholipase c-gamma1 (plcgamma1) defective line is resistant, cells defective in t-cell receptor signaling are still sensitive to pci-34051 induced apoptosis.storage
-20°CPCI 34051 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 119)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from PCI 34051 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-12-24 | N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
950762-95-5
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co | |
 |
2020-12-23 | N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
950762-95-5
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
-
- N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
950762-95-5
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co
-
- N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
950762-95-5
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co
950762-95-5(PCI 34051)Related Search:
N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide
PCI 34051
PCI-34051
1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide
1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-
N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide
PCI-34051;PCI 34051
N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
950762-95-5
Apoptosis
Aromatics
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals
Inhibitor