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Homovanillic acid

CAS No.
306-08-1
Chemical Name:
Homovanillic acid
Synonyms
HVA;Homovanilic acid;4-HYDROXY-3-METHOXYPHENYLACETIC ACID;4-Hydroxy-3-methoxybenzeneacetic acid;Benzeneacetic acid, 4-hydroxy-3-methoxy-;JACS-306-08-1;homovanillicaci;Vanilacetic acid;HOMOVANIUIC ACID;HOMORANILLIC ACID
CBNumber:
CB7198081
Molecular Formula:
C9H10O4
Molecular Weight:
182.17
MDL Number:
MFCD00004350
MOL File:
306-08-1.mol
MSDS File:
SDS
Last updated:2024-10-16 17:43:51

Homovanillic acid Properties

Melting point 142-145 °C(lit.)
Boiling point 235.56°C (rough estimate)
Density 1.1634 (rough estimate)
refractive index 1.4209 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Crystalline Powder
pka 4.39±0.10(Predicted)
color White to beige
Water Solubility soluble
Merck 14,4740
BRN 2213447
Stability Hygroscopic
LogP 0.330
CAS DataBase Reference 306-08-1(CAS DataBase Reference)
FDA UNII
NIST Chemistry Reference
EPA Substance Registry System

SAFETY

Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10-23
TSCA  T
HazardClass  IRRITANT
HS Code  29189900
NFPA 704
0
0 0

Homovanillic acid price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H1252 Homovanillic acid Fluorimetric reagent 306-08-1 1g $92.7 2025-03-01 Buy
Sigma-Aldrich 69673 Homovanillic acid analytical standard 306-08-1 25mg $71.4 2025-03-01 Buy
TCI Chemical H0339 4-Hydroxy-3-methoxyphenylacetic Acid >98.0%(T) 306-08-1 1g $42 2025-03-01 Buy
TCI Chemical H0339 4-Hydroxy-3-methoxyphenylacetic Acid >98.0%(T) 306-08-1 5g $141 2025-03-01 Buy
Alfa Aesar A12441 Homovanillic acid, 98+% 306-08-1 1g $72.4 2025-03-01 Buy
Product number Packaging Price Buy
H1252 1g $92.7 Buy
69673 25mg $71.4 Buy
H0339 1g $42 Buy
H0339 5g $141 Buy
A12441 1g $72.4 Buy

Homovanillic acid Chemical Properties,Uses,Production

Description

Homovanillic acid (HVA) is a dopamine metabolite. It is formed via deamination of dopamine by monoamine oxidase (MAO) to produce 3,4-dihydroxyphenylacetic acid (DOPAC; ) followed by DOPAC metabolism by catechol-O-methyltransferase (COMT). HVA undergoes hydrogen peroxide-dependent oxidation in the presence of horseradish peroxidase to form a fluorescent dimer that displays excitation/emission maxima of 312/420 nm, respectively. It has been used to quantify hydrogen peroxide production in macrophages and neutrophils.

Chemical Properties

white to beige crystalline powder

Uses

A neuroendocrine tumor marker. Dihydroxyphenylacetic Acid (DOPAC) metabolite.

Uses

Fluorimetric reagent and major catecholamine metaboliteHomovanillic acid is used as a reagent in the determination of oxidative enzymes. It is associated with dopamine levels in the brain. Its presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.

Definition

ChEBI: A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Biological Activity

Fluorimetric reagent and major catecholamine metabolite. Used for fluorimetric determination of oxidative enzymes including glucose oxidase.

storage

+4°C
55-10-7
306-08-1
Synthesis of Homovanillic acid from 4-Hydroxy-3-methoxymandelic acid
Global( 390)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
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+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58

View Lastest Price from Homovanillic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-10-16 Chromic sulfate
306-08-1
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-09-06 Homovanillic acid
306-08-1
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-09-06 2-Fluoroethanol
306-08-1
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • Homovanillic acid
    306-08-1
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • 2-Fluoroethanol
    306-08-1
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
4-hydroxy-3-methoxy-benzeneaceticaci 4-hydroxy-3-methoxy-Benzeneaceticacid Acetic acid, (4-hydroxy-3-methoxyphenyl)- Homovanillinic acid Vanilacetic acid Vanillacetic Acid RARECHEM AL BO 0135 4-HYDROXY-3-METHOXYPHENYLACETIC HOMORANILLIC ACID HomovanillicAcid98% 3-METHOXY-4-HYDROXYPHENYL ACETIC ACID HOMOVANIUIC ACID HOMOVANILLIC ACID Homovanillic acid 4-Hydroxy-3-methoxyphenylacetic acid 2-(4-hydroxy-3-methoxy-phenyl)acetic acid HOMOVANILLIC ACID(RG) Benzeneaceticacid,4-hydro 4-HYDROXY-3-METHOXYPHENYLACETIC ACID (HOMOVANILLIC ACID) HOMOVANILLIC ACID extrapure 4-Hydroxy-3-methoxyphenylacetic acid, HVA 3-Methoxy-4-hydroxybenzeneacetic acid Homovanillic acid,4-Hydroxy-3-methoxyphenylacetic acid, HVA 4-Hydroxy-3-Methoxy-α-toluic acid HoMoprotocatechuic acid 3-Methyl ether HoMovanillic acid, 98% 1GR Homovanillic acidFluorimetric reagent≥ 99% (GC) 2-(4-hydroxy-3-methoxyphenyl)acetate JACS-306-08-1 4-Hydroxy-3-methoxyphenylaceticAcid> homovanillicaci 4-Hydroxy-3-methoxy-α-toluic acid Homovanillic acid 306-08-1 4-Hydroxy-3-methoxybenzeneacetic acid Homovanilic acid 4-HYDROXY-3-METHOXYPHENYLACETIC ACID HVA Benzeneacetic acid, 4-hydroxy-3-methoxy- Dopamine Impurity 81 (Homovanillic Acid) 306-08-1 HOC6H3OCH3CH2CO2H chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Multisubstituted Benzene Pharmaceutical Intermediates Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals
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