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ChemicalBook >> CAS DataBase List >>5-Hydroxyindole

5-Hydroxyindole

CAS No.
1953-54-4
Chemical Name:
5-Hydroxyindole
Synonyms
1H-INDOL-5-OL;5-INDOLOL;5-Hydroxyindoline;NSC 87503;INDOL-5-OL;5-hdroxyindole;5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
CBNumber:
CB9151600
Molecular Formula:
C8H7NO
Molecular Weight:
133.15
MDL Number:
MFCD00005677
MOL File:
1953-54-4.mol
MSDS File:
SDS
Last updated:2025-04-22 16:39:17

5-Hydroxyindole Properties

Melting point 106-108 °C(lit.)
Boiling point 245.66°C (rough estimate)
Density 1.1475 (rough estimate)
refractive index 1.5260 (estimate)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 38g/l
form Crystalline Needles or Powder
pka 9.98±0.40(Predicted)
color beige
Sensitive Light Sensitive
BRN 112349
CAS DataBase Reference 1953-54-4(CAS DataBase Reference)
EWG's Food Scores
FDA UNII
NIST Chemistry Reference

SAFETY

Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  NM2430000
HazardClass  IRRITANT, KEEP COLD
HS Code  29339990
NFPA 704
1
2 0

5-Hydroxyindole price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H31859 5-Hydroxyindole 97% 1953-54-4 1g $68.5 2025-03-01 Buy
TCI Chemical H0252 5-Hydroxyindole >98.0%(GC) 1953-54-4 100mg $18 2025-03-01 Buy
TCI Chemical H0252 5-Hydroxyindole >98.0%(GC) 1953-54-4 1g $57 2025-03-01 Buy
Alfa Aesar L00858 5-Hydroxyindole, 98+% 1953-54-4 1g $50.65 2025-03-01 Buy
Alfa Aesar L00858 5-Hydroxyindole, 98+% 1953-54-4 5g $185.65 2025-03-01 Buy
Product number Packaging Price Buy
H31859 1g $68.5 Buy
H0252 100mg $18 Buy
H0252 1g $57 Buy
L00858 1g $50.65 Buy
L00858 5g $185.65 Buy

5-Hydroxyindole Chemical Properties,Uses,Production

Chemical Properties

beige to brown crystalline needles or powder

Uses

• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6

Uses

5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.

Uses

5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptop han (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.

Definition

ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite.

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5579, 1954 DOI:
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI:

1006-94-6
1953-54-4
Synthesis of 5-Hydroxyindole from 5-Methoxyindole
Global( 424)Suppliers
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View Lastest Price from 5-Hydroxyindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2025-04-22 5-Hydroxyindole
1953-54-4
US $10.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2025-03-29 5-Hydroxyindole
1953-54-4
US $8.00-1.00 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-10-18 5-Hydroxyindole
1953-54-4
US $20.00-1.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • 5-Hydroxyindole
    1953-54-4
  • US $10.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • 5-Hydroxyindole
    1953-54-4
  • US $20.00-1.00 / kg
  • 0.99
  • Hebei Yanxi Chemical Co., Ltd.
5-Hydroxy-1H-indole Hydroxy-5 indole hydroxy-5indole TIMTEC-BB SBB004214 5-HYDROXYINDOLE INDOL-5-OL Hydroxyindole,98% 5-hdroxyindole 5-HYDROXYINDOLE 99% 5-Hydroxyindole, 98+% 5-HYDROXYINDOLE (5OHI) 5-Hydroxyindole,97% 5-Hydroxyindole,5-Hydroxyindole, 5-Indolol 5-Hydroxyindole, 97% 1GR NSC 87503 5-carboxylindoline 2,3-dihydro-1h-indole-5-carboxylic Acid Indoline-5-carboxylic acid in stock Factory 5-Hydroxy-1H-indole 98% 5-Hydroxyindole> 5-Hydroxyindole ISO 9001:2015 REACH 1H-INDOL-5-OL 5-INDOLOL 5-Hydroxyindoline 5-Hydroxyindole?New 5-Hydroxyindole, ≥ 98.0% 1953-54-4 1593-54-4 1953-94-4 Building Blocks Indoles Simple Indoles Heterocyclic Building Blocks Heterocycle-Indole series Building Blocks C7 to C9 Chemical Synthesis Heterocyclic Building Blocks Indoles Simple Indoles pharmacetical Indole indole derivative Indoles and derivatives blocks IndolesOxindoles
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