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ChemicalBook >> CAS DataBase List >>Methyl indole-3-carboxylate

Methyl indole-3-carboxylate

CAS No.
942-24-5
Chemical Name:
Methyl indole-3-carboxylate
Synonyms
METHYL 1H-INDOLE-3-CARBOXYLATE;3-Methoxycarbonylindole;methyl indoline-3-carboxylate;INDOLE-3-CARBOXYLIC ACID METHYL ESTER;1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER;RARECHEM AH BS 0112;3-Carbomethoxyindole;Oxiracetam Impurity 38;3-indole,Methyl forMate;Tropisetron Impurity 23
CBNumber:
CB9385281
Molecular Formula:
C10H9NO2
Molecular Weight:
175.18
MDL Number:
MFCD00189407
MOL File:
942-24-5.mol
MSDS File:
SDS
Last updated:2024-10-23 17:13:05

Methyl indole-3-carboxylate Properties

Melting point 149-152 °C (lit.)
Boiling point 306.47°C (rough estimate)
Density 1.1999 (rough estimate)
refractive index 1.5060 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 15.42±0.30(Predicted)
color Light Pink
Water Solubility Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water.
BRN 142023
CAS DataBase Reference 942-24-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
GHS07
Signal word  Warning
Hazard statements  H315-H319-H402
Precautionary statements  P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

Methyl indole-3-carboxylate price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 395307 Methyl indole-3-carboxylate 99% 942-24-5 25g $78.5 2024-06-20 Buy
TCI Chemical I0491 Methyl Indole-3-carboxylate >98.0%(GC) 942-24-5 25g $35 2025-03-01 Buy
TCI Chemical I0491 Methyl Indole-3-carboxylate >98.0%(GC) 942-24-5 500g $377 2025-03-01 Buy
Alfa Aesar L14516 Methyl indole-3-carboxylate, 99% 942-24-5 25g $45.65 2025-03-01 Buy
Alfa Aesar L14516 Methyl indole-3-carboxylate, 99% 942-24-5 100g $150.65 2025-03-01 Buy
Product number Packaging Price Buy
395307 25g $78.5 Buy
I0491 25g $35 Buy
I0491 500g $377 Buy
L14516 25g $45.65 Buy
L14516 100g $150.65 Buy

Methyl indole-3-carboxylate Chemical Properties,Uses,Production

Chemical Properties

light brown amorphous powder

Uses

Reactant for preparation of:

  • Nitric oxide synthase (nNOS) inhibitorS
  • Protein kinase c alpha (PKCα) inhibitors
  • Inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents
  • Kinase insert domain receptor (KDR) inhibitors
  • Organocatalysts for the anti-Mannich reaction
  • Very late antigen-4 (VLA-4) antagonists
  • Inhibitors of Human 5-Lipoxygenase
  • Serotonin 5-HT4 receptor antagonists
  • Hyaluronidase inhibitors

Reactant for:
  • Enantioselective Meerwein-Eschenmoser Claisen rearrangement reactions?

Uses

Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II.

Definition

ChEBI: Methyl indole-3-carboxylate is the methyl ester of indole-3-carboxylic acid. It has a role as a metabolite. It is a member of indoles and a methyl ester. It is functionally related to an indole-3-carboxylic acid.

General Description

Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter-molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate.

Global( 305)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12455 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21698 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8136 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
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Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10828 58

View Lastest Price from Methyl indole-3-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-10-23 Methyl indole-3-carboxylate
942-24-5
US $30.00-10.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-10-09 Methyl indole-3-carboxylate
942-24-5
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-09-06 Methyl indole-3-carboxylate
942-24-5
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
Methyl 3-indolecarboxylate Methyl indole-3-carboxylate, 99% 50GR METHYL-(3-INDOLCARBOXYLATE) FOR SYNTHESI INDOLE-3-CARBOXYLIC ACID METHYL ESTER(I3CAMe) Indole -3-Methyl forMate 3-indole,Methyl forMate Indole-3-carboxylicacidmethylester,99% 3-Carbomethoxyindole Methyl indole-3-carboxylate 99% METHYL INDOLE-3-CARBOXYLATE METHYL-(3-INDOLCARBOXYLATE) 3-Indolecarboxylic acid methyl ester RARECHEM AH BS 0112 Methylindole-3-Carboxylate99% Methyl indolyl-3-carboxylate MethylIndole-3-carboxylate> TIANFU 942-24-5 Methyl indole-3-carboxylate 3-Methoxycarbonylindole INDOLE-3-CARBOXYLIC ACID METHYL ESTER METHYL 1H-INDOLE-3-CARBOXYLATE 1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER methyl indoline-3-carboxylate Tropisetron Impurity 23 Oxiracetam Impurity 38 942-24-5 842-24-5 42-24-5 Heterocyclic Building Blocks Building Blocks Indoles Simple Indoles Heterocycle-Indole series Indoles Simple Indoles Building Blocks Heterocyclic Building Blocks Indoles and derivatives Heterocycles series IndoleDerivative Indole
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