4'-ヒドロキシアセトフェノン 化学特征,用处語,生産方式
外観
红色~わずかにうすい褐色, 結晶~粉末
定義
本品は、次の化学式で表される有機化合物である。
消融性
水に可溶。エタノールに溶けやすく、水に溶けにくい。
用处
有機分解质料。
化粧品の成份用处
酸化避免剤
利用上の注重
不活性ガス封入
化学的特征
almost white to beige crystalline powder
自然物の发源
Reported found in cloudberry, coffee, cranberry, mango, sherry, and wort.
利用
4?-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
製造方式
Preparation by Fries rearrangement of phenyl acetate with Lewis acids
aluminium chloride
in nitrobenzene at 20–25° or at 50–60°
in chlorobenzene between 45° and 65°, sealed tube and subjected to high power microwave irradiation for 2 min only (36%)
in nitroethane at 60° (44%)
in carbon disulfide at 45° (40%)
in petroleum ether at 50° (20%)
but between 130° and 175° (40–60%)
aluminium chloride–sodium chloride mixture at 240–250° (10%)
boron trifluoride at 90° (56%)
scandium tris(trifluoromethanesulfonate), in nitromethane, at 50° (39%)
titanium tetrachloride at 90–100° (34%)
ferric chloride at 65° (25%)
zinc chloride at 125° (8%)
hydrofluoric acid, between 20° and 100° (94%)
polyphosphoric acid, between 20° and 100° (69%) (50–53%)(44%)
Nafion-XR 500, sulfonic acid type at 100°
ZSM-5, in sulfolane, at 180° (28%)
H-ZSM-5 at 400° or at 210° (6%)
H-Nu-2 at 170° (15%)
HY (Si/Al = 3) or fluorided alumina (Al2O3-F; 3 % wt. F), at 400°.
定義
ChEBI: A monohydroxyacetophenone carrying a hydroxy substituent at position 4'.
普通的な説明
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
純化方式
Crystallise it from diethyl ether, aqueous EtOH or *benzene/pet ether. [Beilstein 8 H 87, 8 IV 339.]
4'-ヒドロキシアセトフェノン 下贱と下贱の製品情報
原资料
準備製品