Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 143 mg/kg
Inhalation: Irritating to respiratory system.
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
This product is or contains a component that is not classifiable as to its carcinogenicity based on its IARC, ACGIH, NTP, or EPA classification.
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Lithium and its compounds are possible teratogens by analogy to lithium carbonate which has equivocal human teratogenic data and positive animal teratogenic data.
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: Not available
Fluoride ion can reduce serum calcium levels possibly causing fatal hypocalcemia.
Fluoride ion can reduce serum calcium levels possibly causing fatal hypocalcemia., Cyanosis and t-wave inversion have occurred in the breast-fed infants of women receiving lithium carbonate therapy., Lithium and its compounds are possible teratogens by analogy to lithium carbonate which has equivocal human teratogenic data and positive animal teratogenic data., burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, Large doses of lithium ion have caused dizziness and prostration, and can cause kidney damage if sodium intake is limited. Dehydration, weight loss, dermatological effects, and thyroid disturbances have been reported. Central nervous system effects that include slurred speech, blurred vision, sensory loss, ataxia, and convulsions may occur. Diarrhea, vomiting, and neuromuscular effects such as tremor, clonus, and hyperactive reflexes may occur as a result of repeated exposure to lithium ion. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Toxicity
LD in guinea pigs (mg/kg): 200 orally, 2000 s.c. (Waldbott)