4'-Methyl-2-cyanobiphenyl
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4'-Methyl-2-cyanobiphenyl 속성
- 녹는점
- 49 °C
- 끓는 점
- >320°C
- 밀도
- 1,17 g/cm3
- 증기압
- 0.014Pa at 20℃
- 인화점
- >320°C
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 결정성 분말
- 색상
- 미색부터 베이지까지
- BRN
- 3605954
- LogP
- 3.5 at 23℃
- CAS 데이터베이스
- 114772-53-1(CAS DataBase Reference)
- NIST
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21/22-36/37/38-48/25/62/51/53-22 | ||
안전지침서 | 22-26-36/37/39-36/37/45/57-20-36 | ||
WGK 독일 | 3 | ||
위험 참고 사항 | Irritant | ||
HS 번호 | 27075000 |
4'-Methyl-2-cyanobiphenyl C화학적 특성, 용도, 생산
화학적 성질
White crystalline powder용도
4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.Synthesis
4'-Methyl-2-cyanobiphenyl is prepared by the reaction of o-cyanobromobenzene and potassium (4-methylphenyl)trifluoroborate. The specific synthesis steps are as follows:General procedure: A mixture of aryl halide (0.5 mmol), potassium aryltrifluoroborate (0.6 mmol), K2CO3 (1.0 mmol), Pd/C (5%; 0.5 mol%), ethanol (3 mL), and distilled water (1 mL) was stirred at 80 °C in air for the time indicated. The reaction mixture was added to brine (15 mL) and extracted with ethyl acetate (4×15 mL). The organic solvent was removed under vacuum, and the product was isolated by short-column chromatography.
4'-Methyl-2-cyanobiphenyl 준비 용품 및 원자재
원자재
준비 용품
4'-Methyl-2-cyanobiphenyl 공급 업체
글로벌( 638)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 16799 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 |
sales05@airuikechemical.com | China | 994 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 3001 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15965 | 58 |
Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 |
sales@richfortunechem.com | China | 303 | 57 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9342 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |